The geometric interpretation of the cross product $\vec{a} \times \vec{b}$ is that it gives us a vector that is perpendicular to both $\vec{a}$ and $\vec{b}$, and has length $\left \| \vec{a} \right \| \left\| \vec{b} \right \| \sin \theta$. Howwever, there are 2 such vectors (which point in the exact opposite direction), so this isn't sufficient. We still require the 'right hand rule' to tell us which specified direction the vector points in.
Specifically, if the points $A, B$ are anti clockwise about the origin, then the vector $\vec{a} \times \vec{b}$ will point out of the page, while the vector $\vec{b} \times \vec{a}$ will point into the page. We can tell which direction the vector is pointing at, but taking the dot product with $(0, 0, 1)$. If $( \vec{a} \times \vec{b} ) \cdot (0, 0, 1) >0$, then the points are anti clockwise. If $( \vec{a} \times \vec{b} ) \cdot (0, 0, 1) <0$, then the points are clockwise. If equality holds, then the vectors are parallel to each other.
If you rather look at the algebraic interpretation of the cross product, then $( a_1, a_2 , a_3 ) \times (b_1, b_2, b_3) = \det \begin{pmatrix} a_1 & a_2 & a_3 \\ b_1 & b_2 & b_3 \\ \vec{i} & \vec{j} & \vec{k} \\ \end{pmatrix}$. In the plane, we have $a_3 =0, b_3 = 0$.
Recall that if points $O, A, B$ are in anti clockwise order, then triangle $OAB$ has positive area equal to $\frac {1}{2} \left | \begin{matrix} 0 & a_1 & b_1 & 0 \\ 0 & a_2 & b_2 & 0 \\ \end{matrix} \right | = \frac {1}{2} (a_1 b_2 - a_2 b_1 )$. As such, the orientation can be described by looking at just the signage of this term, which happens to correspond with the coefficient of vector $\vec{k}$ in $\vec{a} \times \vec{b}$. We can recover this term (and hence it's sign) by looking at $ (\vec{a} \times \vec{b} )\cdot \vec{k}$