I just noticed when reading about comet 67P that there were OSIRIS images taken by the OSIRIS camera on the Rosetta spacecraft. Since those six letters also dominate the name of the spacecraft OSIRIS-REx, I was wondering if there is a backstory here, or if it is only a coincidence or acronym collision.
edit 1: After I initially posted I noticed that there is a new space related video game also called OSIRIS which just won Best Survival game at PAX West 2016. Looks a tiny bit realistic perhaps but since I haven't played any space games since Asteroids (the real one, in an arcade, using quarters) I have no idea.
edit 2: Aboard the upcoming CRS-12 launch is the Penn State University cubest OSIRIS-3U (also here and here)
edit 3: Phys.org's article Astronomers discover S0-2 star is single and ready for big Einstein test describes W. M. Keck Observatory's OH-Suppressing Infrared Imaging Spectrograph (OSIRIS) and Laser Guide Star Adaptive Optics.
edit 4: OSIRIS (Optical Space Infrared Downlink System) highly compact optical communication payloads for small spacecrafts in a LEO 1, 2, 3, 4, 5.