Use the fact that 11322, 13209, 29189, 56661, and 15096 are all divisible by 17 to show that
$$\begin{vmatrix} 1&1&2&5&1\\ 1&3&9&6&5\\ 3&2&1&6&0\\ 2&0&8&6&9\\ 2&9&9&1&6 \end{vmatrix}$$
is divisible by 17 without directly evaluating the determinant.
Use the fact that 11322, 13209, 29189, 56661, and 15096 are all divisible by 17 to show that
$$\begin{vmatrix} 1&1&2&5&1\\ 1&3&9&6&5\\ 3&2&1&6&0\\ 2&0&8&6&9\\ 2&9&9&1&6 \end{vmatrix}$$
is divisible by 17 without directly evaluating the determinant.
The determinant of a matrix after adding a multiple of one row to another remains the same.
So you can add $10^4$ of the first row, $10^3$ of the second, $10^2$ of the third and $10^1$ of the fourth row to the fifth row, and the determinant will be preserved. This will give you the last row as
$$(\begin{matrix}11322 & 13209 & 29189 & 56661 & 15096\end{matrix})$$
Afterwards, do cofactor expansion along the fifth row to get
$$\det = 11322A_{5,1} + 13209A_{5,2} + 29189A_{5, 3} + 56661A_{5, 4} + 15096A_{5, 5}$$
which is divisible by $17$ by the divisibility of linear combinations.
$$ \begin{vmatrix} 1 & 1& 2& 5& 1\\ 1 &3&9&6&5 \\ 3&2&1&6&0\\ 2&0&8&6&9\\ 2&9&9&1&6 \end{vmatrix} = 10^{-10}\begin{vmatrix} 1 \times 10^4 & 1 \times 10^4& 2\times 10^4& 5\times 10^4& 1\times 10^4\\ 1\times 10^3 &3\times 10^3&9 \times 10^3&6 \times 10^3&5 \times 10^3 \\ 3 \times 10^2&2\times 10^2&1\times 10^2&6 \times 10^2&0 \times 10^2\\ 2 \times 10&0 \times 10&8 \times 10&6 \times 10&9 \times 10\\ 2&9&9&1&6 \end{vmatrix} \\ = 10^{-10}\begin{vmatrix} 11322 & 13209& 29189& 56661& 15096\\ 1\times 10^3 &3\times 10^3&9 \times 10^3&6 \times 10^3&5 \times 10^3 \\ 3 \times 10^2&2\times 10^2&1\times 10^2&6 \times 10^2&0 \times 10^2\\ 2 \times 10&0 \times 10&8 \times 10&6 \times 10&9 \times 10\\ 2&9&9&1&6 \end{vmatrix} $$
by adding to the first row, all the other rows. This is a multiple of $17$ as the top row is a multiple of $17$. Furthermore, since the first determinant is an integer, the rest also are integers, despite the fact that there is a division by $10^{-10}$.
As if to confirm, the answer to this determinant is $1666 = 98 \times 17$.
If $M$ is your matrix, considered over the field $\mathbb Z/17 \mathbb Z$, these facts tell you that $$M^T \pmatrix{10^4\cr 10^3\cr 10^2\cr 10\cr 1\cr} = 0 $$ and therefore that $M$ is not invertible over that field.