Presumably you mean "and make untrue accusations of wrong-doing". In the US, defamation involves statements about a legal person, and a place, government or government body, or industry is not a legal personal (a specific business can be, however). In the course of "defaming" a city, you might end up defaming a supposedly fictitious individual who bears a striking resemblance to a real person, for example a made-up New York real estate tycoon named Ronald Rump who runs for president. Or you could defame the "police department of Bug Tussle" which in fact is composed of only one person -- that is, you refer to a group but the group is so small that it actually refers to an identifiable individual. See this answer regarding defaming people in fiction.
Okay, it's not actually true that a government can't be a legal person. The fact that in the US a government can't sue for defamation would be rooted in the First Amendment, and is surely embodied in case law that is lurking. In Canada, governments have had more power to pursue critic via defamation suits. In Ontario, Halton Hills (Town) v. Kerouac 80 O.R. (3d) 577 (2006) says that "a government may not sue in defamation". I expect that there is some such ruling in the history of US law.