The Di(c)e is unlocked after beating Mom's heart while in the ???-form. I tried again and again, but somehow even fail to make it to Mom. This made me think: There must be some strategies I could apply to raise my chances.
Thoughts so far:
- Since ??? doesn't benefit from Red Hearts, items like Mitre or Mom's Pearl can help a lot
- Devil Room items always cost three Soul Hearts, so it might be wise to visit and skip to raise the odds of an Angel Room appearing
- Maybe it's clever to only try to go for the treasure room (and obvious (super)secret rooms) in each floor before heading to the boss. I'd miss out on items but preserve my precious Soul Hearts
- To unlock The Die it's not necessary to start the game as ???, since the Ankh can be used to transform into ??? just before visiting Mom's Heart.
There might be some items that work well together, some items I have to find early in the game to even go on with the run or even strategic poop placement.
Is there a single combination of items or a single playpattern that helps preserve life and make it to Mom's Heart?