A full-time job usually involves a very large time commitment to a very narrow interest. Both "blue" and "white" collar workers spend 40+ hours a week performing specific sets of tasks. Labor is highly specialized, and people are expected to devote large amounts mental energy following through with the rules and details of their assigned projects.
This DSM5 excerpt summarizes autism as two general traits: social deficiency and restricted sets of interest. The former of course a significant problem while on the clock, but the latter seems to be a mixed bag.
Hyper-reactivity to sensory stimuli can cause issues, if present. However, "excessive adherence to routines" and "perseverative interests" are the bread and butter of most full-time jobs. If anything, "neurotypicals" should struggle to maintain such a laser focus. Given how we organized most of our economy and society around full-time employment, why would "restricted interests" be considered "symptoms" of autism?