I thought that since grignards are such strong bases that they would be immediately protonated by the alpha hydrogen since it is an acidic hydrogen. However, I keep seeing answers that are saying that they just add to the carbonyl. I understand that they are strong bases, and therefore make bad leaving groups (forming a stable tetrahedral compound) once they add to the carbonyl, but I don't understand why they would add rather than deprotonate.
Asked
Active
Viewed 23 times
0
-
https://chemistry.stackexchange.com/questions/134270/grignard-reagent-will-act-as-a-base-or-a-nucleophile https://chemistry.stackexchange.com/questions/113023/grignard-reagent-and-acidic-hydrogen – Mithoron Oct 11 '23 at 22:44