Questions tagged [mrna]

Messenger RNA is produced during transcription before it leaves the nucleus to be be translated by a ribosome. This produces a sequence of nucleic acids for which mRNA is considered the template.

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Are RNA cleavage sites always polyadenylated?

During RNA processing (including both mRNA and non-coding RNAs), is the end of 3'UTR always polyadenylated after cleavage? I could not find the answer to my question in the Wikipedia entry for polyadenylation. If a recent reference could be…
zyxue
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Why is the 3'UTR AES of the Pfizer/BioNTech vaccine preceded by a CUC GAG?

According to the WHO submission and one of the preprints from BioNTech/Pfizer, the 3'UTR of their Covid-19 vaccine's mRNA is the combo of the AES and mtRNR1 sequences, which (in the preprint) BioNTech cites to a paper on library screening of 3'UTRs…
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mRNA bonding to itself

Does a mRNA molecule bond to itself? I heard that only tRNAs have hydrogen bonds that let them have second structures, but after searching the web i found multiple answers. If yes, does anybody have a credible reference for that?(books, articles…
user47496
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Why is the mRNA not damaged at -70 C temperature Corona vaccine?

Why is the mRNA not damaged at -70 C temperature Corona vaccine? Need for -70 degree temperature for Corona vaccine I assume that if I, for example, were to freeze, say, a chicken egg after heating to room temperature, the protein binding would be…
user1785960
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