The study of the electrical properties of biological cells and tissues.
Questions tagged [electrophysiology]
180 questions
6
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1 answer
Shouldn't recording electrode have as low resistance as possible?
Following quote is from this wikipedia page on single unit recording.
Intracellular single unit recordings require electrodes be inserted through the cell membrane to record from within the cell. Glass micropipettes or metal electrodes may be used…
bhyjnikm
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3
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How much current is required to stimulate a neuron?
Extracellular stimulation of neural tissue is done using electrode. Amount of current determines neurons how far from the electrode will be excited. How much current is required to stimulate the neuron in immediate vicinity? Such information is not…
ertyu
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3
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At which voltage will the conductance decrease due to the narrow pore in a voltage-gated potassium channel?
If you have a voltage-gated potassium channel that do not inactivate, at which voltage would you see decrease in ion conductance related to the narrow path in the pore?
With that said I know that in a solutions with other ions there is a…
Plutoid
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2
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What is the standard electrode potential of human blood?
Healthy humans have a pH of around 7.4 (slightly basic.) But if you hooked up the blood as a battery how much electric voltage would one generate, what is the standard electrode potential?
This seems to me like it should be important for stuff such…
Molly Stewart-Gallus
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2
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How the electrons from electrode play a role in stimulating the neuron?
I am trying to understand how a neuron fires action potential after being stimulated via electrode (extracellular stimulation). GHK equation gives the membrane potential,which is -70 mV when neuron is at rest. When the membrane potential increases…
dfghj
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2
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Why does high-voltage mostly shock a person, and even small current kill?
This may be the wrong forum to ask.
For instance several people are known to have survived a direct lightning strike; albeit the number of fatalities are probably far larger. Anyway, I found myself wondering why high-voltage may shock a person and…
Everyone
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What is the resistance of a single human cell?
What is the resistance of a single human cell? I know different cells will have different values, some examples would suffice. I did not find any such information on the internet.
poi
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What will happen to a neuron if I suddenly remove the pump but not the leaky Na+ and K+ channels?
K+ is more abundant inside the cell and thus has a propensity to move outwards. It has an equilibrium potential of -80 mV. Na+ is more abundant extracellularly and thus has a propensity to move inwards. It has an equilibrium potential of 58 mV. The…
Black Dagger
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Electrodes for electroporation of bacterial cells
Wikipedia says
"The process {electroporation} requires direct contact between the electrodes and the suspension."
However I've read the process is an effect of the field strength alone, and ideally no current passes at all, due to its heating and…
Oliver Walters
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0
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What is a "membrane holding potential"?
What is a membrane holding potential? I have come across this term but haven't been able to find a definition.
From "Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders", legend to Figure…
CopperKettle
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How much electrical energy is required for intracellular stimulation of a neuron?
How much electrical energy is required for intracellular stimulation (firing) of a human neuron? Electrical energy is measured in joules, and equal to voltage multiplied by current. If you don't know energy, you may specify voltage applied and…
azxsw
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-1
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Using Nerve Conduction Studies to determine nerve regeneration
I was reading a paper investigating using MRI as a way to determine peripheral nerve regeneration: https://sci-hub.do/10.1016/j.expneurol.2009.10.012
They mention that
... nerve conduction studies are widely used but these studies are limited
only…
John Hon
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