Questions tagged [antibody]

A protein produced by the B-cells of the immune system which binds to a particular antigen, a foreign substance to the body.

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Antibodies stored in freezer instead of fridge

Someone from my lab put the box of antibodies in the freezer instead the fridge. Can I hope that they will still work?
Anael
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How can cells produce antibodies despite error-checking mechanisms in their genomes?

How can immune cells produce so many different kinds of antibodies with different variable regions if there are so many mechanisms inside the cells that try to keep the DNA sequence as constant as possible (i.e. prevent mutations, which are actually…
ask937
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Why are antibodies so expensive?

The amplification on vector transgenic microorganisms and the subsequent purification does not seem that complicated. Also, what are the processes that biotechnological industries follow, in detail, on their production?
Katz
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What is A in IgA?

What is the significance of letter A in immunoglobulinA? What are the significance of other letters D, M , G, E in diffeternt types of antibodies?
JM97
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Can the body always find the right antibodies?

If the body produces random antibodies in order to fight a virus, is there a small chance that the specific antibody needed to fight the virus just won't be randomly generated? Even though it is a common virus that normally doesn't kill people? For…
zooby
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Why a repeat wasp sting cause an anaphylaxis shock?

I understand that an anaphylaxis shock caused by a huge dose of histamine. But why the first sting does not cause an anaphylaxis shock like the second sting? As i think there may be a relevant between antibody and histamine because the victim…
DucFabulous
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Fab fragments of antibodies to fight viral infections

I was reading about Fab fragment and about using them to fight of viral infections. It seems that the Fab attaches to the viral receptors, which stops the viruses from attacking the cells. It seems that it has been done before. I was wondering,…
TanMath
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What is the difference between monoclonal and polyclonal antibodies?

I'm having trouble to see a difference between monoclonal and polyclonal antibodies. The way I understand it: Monoclonal antibodies are produced by the same "clone" or "line" of B-cells and, thus, can bind to a single epitope for some…
OldCrow
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Do all monoclonal antibodies have a blocking effect?

I find a mAb targeting protein A, which has beed validated to work in wb/IHC/IP or antibody conjugating drugs. I'm wondering if this mAb could be used for blocking the protein A from binding with other proteins? This mAb is the only one antibody…